You don't see many TF2's with 2.2 wheels, so check and double check you'll get clearance. Any tyre imho above 106mm starts to look a bit monster truck.
The stock black leafs with no helpers soon bed in and give great flex after a couple of hours trail time.
ESC wise try to get one that is crawler specific, with drag brake. In the UK we mostly use the mtronics rockc but doubt you have that your side of the pond.